Evolutionary diversification of epidermal barrier genes in amphibians
Abstract The epidermal differentiation complex (EDC) is a cluster of genes encoding components of the skin barrier in terrestrial vertebrates.EDC genes can be categorized as S100 fused-type protein (SFTP) genes such as filaggrin, which contain two coding exons, and single-coding-exon EDC Toy Box (SEDC) genes such as loricrin.SFTPs are known to be p